<?xml version="1.0" encoding="UTF-8"?><rss xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:content="http://purl.org/rss/1.0/modules/content/" xmlns:atom="http://www.w3.org/2005/Atom" version="2.0"><channel><title><![CDATA[GlobalCures]]></title><description><![CDATA[Affordable, advanced cancer treatments — GlobalCures connects Asian patients to CAR-T, Proton, and TIL therapies up to 2-3x cheaper than Singapore /US]]></description><link>https://www.globalcures.net/blog</link><generator>RSS for Node</generator><lastBuildDate>Mon, 24 Aug 2026 09:04:29 GMT</lastBuildDate><atom:link href="https://www.globalcures.net/blog-feed.xml" rel="self" type="application/rss+xml"/><item><title><![CDATA[Sintilimab - Asian-optimized PD-1 checkpoint inhibitor by Lilly and Innovent Biologics]]></title><description><![CDATA[Sintilimab is a fully human IgG4 monoclonal antibody targeting programmed death-1 (PD-1). It is co-developed by Innovent Biologics and Eli Lilly , with clinical development specifically optimized for Asian patient populations . Sintilimab is approved by the National Medical Products Administration (NMPA) of China  for multiple solid tumors and hematologic malignancies. Mechanism of Action Sintilimab binds to PD-1 on activated T cells, blocking interaction with PD-L1 and PD-L2. This releases...]]></description><link>https://www.globalcures.net/post/sintilimab-asian-optimized-pd-1-checkpoint-inhibitor-by-lilly-and-innovent-biologics</link><guid isPermaLink="false">6a89acf05802447f29d3c0fb</guid><pubDate>Wed, 17 Dec 2025 13:19:23 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/8192bb_fddee5bdbbca4a099e7e38c5fda739fb~mv2.jpg/v1/fit/w_298,h_273,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Emmanuel Paredes</dc:creator></item><item><title><![CDATA[Cadonilimab — a PD-1/CTLA-4 bispecific antibody for cervical cancer and other solid tumors]]></title><description><![CDATA[Cadonilimab  is a humanized, tetravalent bispecific monoclonal antibody that simultaneously targets programmed cell-death protein-1 (PD-1) and cytotoxic T lymphocyte–associated protein-4 (CTLA-4). Designed to combine checkpoint blockade at two complementary immune checkpoints in a single molecule, cadonilimab was developed to harness the synergistic antitumor activity of dual checkpoint inhibition while improving safety and tolerability relative to separate PD-1 + CTLA-4 antibody...]]></description><link>https://www.globalcures.net/post/cadonilimab-a-pd-1-ctla-4-bispecific-antibody-for-cervical-cancer-and-other-solid-tumors</link><guid isPermaLink="false">6a89acf05802447f29d3c0fa</guid><pubDate>Sat, 01 Nov 2025 03:17:32 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/8192bb_de8612677b964bc1a7d3e1c3d932bc8d~mv2.png/v1/fit/w_955,h_538,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Emmanuel Paredes</dc:creator></item><item><title><![CDATA[Toripalimab — a PD-1 inhibitor for multiple solid tumors]]></title><description><![CDATA[Toripalimab  is a humanized IgG4 monoclonal antibody that blocks programmed cell death protein-1 (PD-1). It is US-FDA approved for selected indications including recurrent/metastatic nasopharyngeal carcinoma (NPC), and China-NMPA approved for urotheliel carcinoma, esophageal squamous cell carcinoma, non-squamous / resectable stage IIIA-IIIB  NSCLC, ES-SCLC, renal cell carcinoma, and TNBC . Mechanism of Action PD-1 is an inhibitory receptor on activated T cells; binding of PD-L1/PD-L2 to PD-1...]]></description><link>https://www.globalcures.net/post/toripalimab-a-pd-1-inhibitor-for-multiple-solid-tumors</link><guid isPermaLink="false">6a89acf05802447f29d3c0f9</guid><pubDate>Fri, 31 Oct 2025 14:18:04 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/8192bb_8c3876cb9f014a6787994ed6a051d73f~mv2.png/v1/fit/w_600,h_400,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Emmanuel Paredes</dc:creator></item><item><title><![CDATA[Fruquintinib, a US FDA-approved inhibitor for metastatic colorectal cancer ]]></title><description><![CDATA[Fruquintinib, a US FDA-approved inhibitor for metastatic colorectal cancer  Fruquintinib, marketed under the brand name Fruzaqla, is an...]]></description><link>https://www.globalcures.net/post/fruquintinib</link><guid isPermaLink="false">6a89acee5802447f29d3c0f1</guid><pubDate>Mon, 03 Feb 2025 03:55:05 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/8192bb_9e7ab98e56064b7eb26a682d5627691a~mv2.jpg/v1/fit/w_1000,h_1000,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>buildclock</dc:creator></item><item><title><![CDATA[Tislelizumab: US FDA approved with superior efficacy in ESCC]]></title><description><![CDATA[Tislelizumab: superior efficacy in ESCC Tislelizumab is a recombinant humanized IgG4 kappa monoclonal antibody that targets the...]]></description><link>https://www.globalcures.net/post/tislelizumab</link><guid isPermaLink="false">6a89acee5802447f29d3c0f0</guid><pubDate>Mon, 03 Feb 2025 03:43:27 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/8192bb_2e651996ec3d465bb7f8eed86635e4dd~mv2.jpg/v1/fit/w_1000,h_1000,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>buildclock</dc:creator></item><item><title><![CDATA[Ivonescimab - Promising Efficacy in NSCLC]]></title><description><![CDATA[Ivonescimab - Promising Efficacy in NSCLC Ivonescimab, also known as AK112, is a novel bispecific monoclonal antibody that simultaneously...]]></description><link>https://www.globalcures.net/post/ivonescimab</link><guid isPermaLink="false">6a89acee5802447f29d3c0ed</guid><pubDate>Mon, 03 Feb 2025 02:59:24 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/8192bb_ac02519176064478881945687860b538~mv2.png/v1/fit/w_1000,h_1000,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>buildclock</dc:creator></item></channel></rss>